Structural Tissue Allograft

The Structural Foundation
for Surgical Repair

A full-thickness, hydrated placental matrix designed to supplement, repair, and reinforce native tissue—preserving architecture and providing a physical framework for intra-operative support.

Preserved Architecture

Designed for surgery

Workflow Aligned

3-in-1 Allograft System

Full-Thickness Intact by Design.

Hydrated. Not Dehydrated.

Structural by purpose. Built for surgery.

Preserving structure. Supporting the biology of healing.

Structural Tissue Allograft (STA™)

Great surgery restores anatomy. STA™ supports the healing environment. Designed for surgical repair. Built for system-wide adoption.

What STA™ Is: The Structural Foundation

Structural Tissue Allograft (STA) is a full-thickness, hydrated placental matrix designed to supplement, repair, and reinforce native tissue. Unlike particulates or flowables, STA is a structural implant—preserving native architecture and providing a physical framework for intra-operative tissue support.

Preserved Architecture

Designed for Surgery

Workflow Aligned

3-in-1 Allograft System

3-in-1 Structure

One implant. Multiple tissue environments.

  • Structural Implant By Design

    Not a filler. Full-thickness. Ultra-minimally manipulated. Designed to provide a physical framework for surgical tissue support.

  • Architectural Foundation

    Preserves native tissue architecture—including collagen and elastin—maintaining structural continuity across layers.

  • Native Matrix Composition

    361 HCT/P compliant structural scaffold that retains native extracellular matrix components, including fibronectin, laminin, and glycosaminoglycans.

Three structural components. One preserved system.

Purpose-Built For The Surgical Environment

Designed for Structural Support

One implant. Multiple tissue environments.

Structurally Complete. Preserved Native Matrix.

Supports site-appropriate tissue repair across multiple environments.

Tendon & Ligament

Reinforces soft tissue structures.

Cartilage

Provides a structural interface for cartilege repair.

Bone

Supports structural integration in bone repair procedures.

Nerve

Provides a protective interface for delicate neural structures.

Skin / Wound

Provides a protective covering to support wound healing.

One Allograft. Multiple Applications.

Preservation & Biology: The Context For Healing

By preserving the native extracellular matrix in its hydrated state, STA maintains both structural integrity and the native composition of the tissue.This enables the implant to function as a functional structural scaffold, supporting organized tissue repair rather than acting as a passive patch.

Fibronectin & Laminin

A key extracellular matrix component associated with cellular adhesion and migration.

Fibronectin & Laminin

Biological Anchors act as the "biological glue" for cellular attachment. These proteins work alongside FGF and IGF to facilitate rapid migration and organized tissue remodeling across the foundation.

Collagen

Structural continuity and tensile support.

Collagen

Preserves native architecture (Types I, III, IV, V) to provide tensile strength. This framework anchors Growth Factors (PDGF, TGF-β) that trigger the initial stages of cellular recruitment.

Elastin

Elasticity and recoil within the preserved matrix.

Elastin

Mechanical Resilience maintains native fibers for dynamic stretch and recoil. This elastic matrix supports Vascularization (VEGF), ensuring the tissue remains viable and integrated under structural loading.

Proteoglycans & GAGs

Matrix hydration and structural support.

Proteoglycans & GAGs

Hydration & Signaling Context Maintains the moisture required for Anti-inflammatory mediators (IL-10) and manages the Matrix remodeling balance (MMP / TIMP pathways) to ensure a stable healing environment.

Together, these structural components preserve the native tissue environment, supporting organized tissue remodeling.

Processing Determines Performance. Standardization Drives Value

Designed for System-Level Adoption

01

Standardization

Enables consistent product utilization across Orthopedics, Neuro, and General Surgery.

02

Workflow Alignment

Integrates seamlessly into existing implant-based protocols and procurement pathways.

03

Economic Clarity

Minimizes clinical and financial fluctuations through a single, validated platform.

04

Simplification

Reduces inventory redundancy by replacing fragmented, multi-vendor biologic portfolios.

Clarity. Confidence. Alignment.

STA™ is regulated under Section 361 of the Public Health Service Act as a structural tissue allograft intended for homologous use. Its classification has been reviewed by the FDA Tissue Reference Group (TRG), confirming alignment with minimal manipulation & homologous use. This level of regulatory clarity supports efficient Value Analysis Committee review and enables confident adoption across health systems. All products are sourced exclusively from AATB-accredited, FDA-registered tissue banks and processed under controlled conditions.

One Platform. Multiple Clinical Environments.

We are not a biologics company with multiple products. We are a structural tissue repair platform designed for health systems that delivers consistency across surgical, wound, and clinical environments.

Structural Tissue Allograft (STA™) Surgical Implants

STA™  is the anchor of our platform. A full-thickness, hydrated matrix designed specifically for the high-demand environment of the operating room. 

Replaces multiple “boutique” surgical biologics with one validated structural standard.

 

AyoVita™ Advanced Wound Solutions

Extending our core structural technology into the chronic and surgical wound care space. By maintaining the same architectural integrity, AyoVita™ provides the scaffold necessary for complex closure. 

Streamlines the transition from the OR to outpatient wound clinics using a consistent biologic framework.

Nouvelle™ Specialized BioSolutions

Purpose-built structural applications for environments where both structural performance and aesthetic refinement are critical.

Reduces the need for specialized aesthetic vendors by leveraging the existing health system platform.

The most advanced solutions in medicine are not always created, they are preserved.

Preserve Native Structure

Maintaining the full-thickness matrix that surgeons trust.

Maintain Biological Integrity

Protecting the signaling molecules inherent to the tissue.

Deliver Consistent Utility

Ensuring every implant performs with predictable excellence.

Clarity. Consistency. Confidence.
A new standard in tissue repair.

Inquire About Our Platform Today