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Structural Tissue Allograft (STA™)

Preserving structure. Supporting the biology of healing.

Learn About STA™

Great surgery restores anatomy.

STA™ supports the healing environment.

Designed for surgical repair.

Built for system-wide adoption.

Problem

Why biologics fall short in surgical repair.

  • Loss of structural integrity during processing
  • Loss of native extracellular matrix composition
  • Repurposed products designed for wound coverage, not surgical repair
  • Inconsistent clinical and economic outcomes

*Most biologics were not designed to provide structural support in surgery.

Solution: STA™

Designed for Implantation

Purpose-Built for Intra-Operative Tissue Repair—Not Adapted from Wound Care.

What STA™ is

A structural tissue implant
not a repurposed biologic

Full Thickness Structure

Multi-layer placental connective tissue, preserved in its native architecture

Designed for Implantation

Built for intra-operative placement—not repurposed for wound coverage

361 HCT/P Aligned

Ultra-minimally manipulated structural tissue allograft consistent with updated regulatory guidance

Total-Body Application

Supports repair across multiple tissue types within a single structural platform

Processing Determines Performance

The way tissue is processed defines what remains—structure, signaling, and biologic function.

PROCESS

Controlled Processing

Precision handling designed to preserve native tissue integrity. 

PRESERVATION

Structural Preservation

Native architecture maintained across full-thickness tissue layers.

PAYLOAD

Native Tissue Composition

Extracellular matrix components retained within the preserved structure.

PERFORMANCE

Functional Support

Designed to support the body’s natural tissue repair process. 

STRUCTURAL PRESERVATION MAINTAINS TISSUE COMPOSITION TO SUPPORT FUNCTIONAL REPAIR.

Hydration preserves the biologic system

Unlike dehydrated grafts, STA™ maintains a hydrated environment— supporting diffusion, signaling, and integration.
Platform overview

Three Platforms. One Structural Foundation

A Unified Approach to Structural Tissue Repair 

Each platform is purpose-built for its unique clinical environment, unified by the same structural philosophy. 
Together, they form a cohesive, system-wide approach to tissue repair, designed for clinical integration and institutional scale.

STA™

Structural Tissue Allograft Surgical Implants

AyoVita™

Structural Support for Complex Wound Environments

Nouvelle™

BioSolutions for Contemporary Clinical Practice

Gratitude as a Catalyst for Growth and Renewal

Gratitude Therapeutics was founded on a simple belief:

  • That progress in medicine should extend beyond the procedure itself.
  • Every product represents not only a clinical tool—but an opportunity to create broader impact.
  • A portion of our work supports individuals and communities seeking a fresh start.
  • Because growth and renewal are not only biological principles, they are human ones.
  • And the same philosophy that guides constructive tissue remodeling, structure, balance, and preservation, also guides how we build this company.

A platform designed to restore structure.

A philosophy grounded in respect for biology.

A partner built for long-term clinical adoption.

Built for Surgeons. Scaled For Health Systems.

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